Monday, September 30, 2019

Effects of Globalization on the Environment Essay

Globalization has had a huge impact on the world in a number of ways. It has increased the integration of countries’ individual economies, the rise in the world trade and multinational companies, and the effect of large amounts of money moving in and out of economies throughout the world. People around the world are more connected to each other than ever before. Information and money flow more quickly than ever before. In addition goods and services produced in one part of the world are increasingly available in all parts of the world. International travel and communication in now more frequent and has become commonplace throughout the world. It can not be denied that globalization has had an overwhelming positive influence. Millions of jobs have been opened up through the ever increasing productivity and efficiency of the global economy. Globalization for less developed countries has encouraged faster growth, in turn promoting poverty reduction, democratization and higher labor and environmental standards. It also gives citizens greater individual freedom to express views and experience cultures through such mediums as television and the internet, which encourage understanding around the world. This fairly new glorified issue has had a great impact on the global environment in addition to all other aspects of the world that it has affected. One of the greatest examples that come to mind is the endless support of the tsunamis victims. Without globalization the world could not have contributed to the extent of what we have. Relentless support has been granted to the victims of this tragic event in record time. Globalization has made this possible through the increase in technology and communication. Citizens of the world now have the ability to contribute time, money and supplies to countries that would otherwise be stranded or left hanging for a period of time. Our valiant efforts have put this epic event at an all time support relief. We are now able to send support in all forms more conveniently. Without the effects of globalization this event that has occurred would have been much more devastating. The world can thank globalization for this never ending support. In addition to the tsunamis relief support granted through globalization, it has affected the environment in other ways as well. It has greatly increased the environmental standards worldwide. Through the development of the internet many environmental agencies have evolved which have increased the protection of the environment. The internet has made them more effective and they are now able to communicate much easier than ever before. Through the development of environmental supports some beneficial factors have evolved such as new up to date emissions standards. This greatly reduces the worldwide threat of global warming. By agencies effectively implementing such standards our world has become safer and healthier. These efforts are now on a continuum which only leaves our world to improvement. Globalization is the reason for this and without it our world would be at risk of inevitable destruction. Through the efforts of environmental agencies we as a world are now aware and informed of the dangers of what used to be every day practices. We can thank the rise of globalization for our continuing efforts for world wide environmental improvement.

Sunday, September 29, 2019

Sammy will definitely feel this event all his life

The basic plot of John Updike’s A & P is that Sammy clerks in a grocery store.   Stokesie is a young man who also works at the store, but he is there to support his family.There are some bold girls that come into the store and are frowned upon by the management.   The girls are dressed in beach attire and when Lengel (the manager) refuses to serve them, Sammy quits his job.   Lengel warns him â€Å"You’ll feel this for the rest of your life,† (Updike) and Sammy agrees.Sammy will definitely feel this event all his life.   By quitting his job, he is rejecting Lengel and his middle-class, uptight attitude.  Ã‚   In Sammy’s mind, the girls should be able to come in dressed in beach ware and not be judged.   Frivolous behavior should be tolerated and not frowned upon.  Ã‚   If they are dressed to scantily and cause people to look at them, that’s okay.   They’re young.   If men look at them, that is okay too.   It’s okay to look at pretty girls without feeling guilty.Sammy really grows up throughout the course of the story.   As Sammy walks away from the store he realizes â€Å"how hard the world was going to be to me hereafter† (Updike).   Sammy realizes that much of the world is filled with people who think like Lengel, and that he will be the one to buck the system.   He is not willing to go along with the status quo, and that will make his life difficult.The Lengels of the world are just too narrow to simply enjoy watching a pretty girl.   Sammy will be able to enjoy those simple pleasures without condemning them.In rejecting Lengel’s values, he is also rejecting the values of his family or his circle of society.   He decides that he wants more in life than vying for a manager position in an A & P.   He refers to the shoppers as â€Å"sheep† and decides that he does not want to be a sheep.The girls in their swimsuits simply help bring about that epiphany.   Sam my has really won according to his own values, but in the minds of many others, he has lost.   Everyone will know that he quit.   His parents will most likely be disappointed and might think his reasons frivolous.   It is only the beginning of bucking the system for Sammy.Works CitedUpdike, John.   A & P.

Saturday, September 28, 2019

Luxury vehicle Essay

1. Cadillac introduced it’s new luxury SUV that is called the Escalade, and they had no idea in what direction it would lead to. To their surprise, it becomes a instant classic and the most popular truck on the market. They weren’t set out to target a specific customer base, they just wanted to keep up with the SUV craze. They saw other companies putting out similar vehicles, so they wanted to dip into that market. Once it released, it seemed to become a staple in the hip hop community, sports world, and for regular customers looking for a luxury SUV. It became most prominent however in the hip hop and sports cultures. You see tons of athletes arriving to the games in their escalades, and a lot of hip hop artists have them featured in their music videos. For some reason, it just excelled in the market, and there is really no particular reason for it. It could be because of how unique it looks, the luxurious features, or just off the time it was released. The music and sports industry started to boom so there was a lot of money to be spent and the Escalade was the newest and hottest item on the street. 2. The Escalade became so popular I believe for the power it represents. I feel that if you own a Escalade, you have a sense of power in a way. Whether it shows that you have money, a sense of style, or anything else, it just brings off a certain type of vibe. It shows some type of boldness as well, because you think of personality when you think of an Escalade. When you look at one, you notice first how the shiny grill stands out and just how luxurious the car is. I think in a way Cadillac has extended its appeal because now a lot of the Cadillacs feature the shiny grill. You also see its influence on other vehicles, because a lot of competitors base their models off of it and try to make some similarities. 3. Other companies have a lot to learn from the Escalade. If they do it right, maybe they can become the leader in luxury SUVs. It’s all about whom you have to endorse your product and how you market it out to the public. Cadillac know it has many endorsers that are famous and widely known throughout the world. When you have people of that magnitude openly using your products, you gain a tremendous amount of recognition. Also, before you come up with a new concept or design, you should allow potential customers to see the product to see if it would be something they would like. If you market your product correctly, there is a good chance that it will be successful just like the Cadillac Escalade. Case Study Cadillac is one of the most popular vehicle brands in the United States to this date. As Americans, we tend to treat it differently because it is the luxury brand of our Country. Since it is an American made car, we take a sense of pride in it, and owning one is something special. In 1998 there started to be a craze for mid size SUVs, and just like every other vehicle company, Cadillac had some thoughts in mind. They released their brand new line of the Cadillac Escalade, a large luxurious SUV. When they originally released it, they felt that their market would be traditional customers, but boy, where they wrong. In fact, it was the complete opposite. The Escalade seemed to become nationally recognized when it was constantly featured in hip hop videos, commercials, and the sports industry. While Cadillac didn’t intend to get into those specific markets, I’m sure they aren’t complaining because of how much recognition it gave them. However, it does seem to brush off a certain bad image when you see it featured in some of those ways. When you see a Escalade in a hip hop video that has drugs, half naked women, and curse words, it may rub some of your other customers off. It can be seen as a gang car, and you certainly don’t want to be driving one of those in certain areas. A regular family can be in the market for a SUV, but they may get a negative vibe from the Escalade because it may come off as being too â€Å"hood† or â€Å"ghetto† for them. I’m not too sure how a car can gain that characteristic, but I understand by it being featured and abused in certain ways, it can portray a negative image. Cadillac can feature their products in certain ways, and be able to be seen as a positive vehicle that is made for everybody. They can limit their exposure in hip hop videos if they feel that is necessary. When you see certain commercials you notice that the brand symbol is blurred out. If Cadillac saw this as a dilemma, they can gain access to have their emblems blurred out in rap videos that feature bad behavior. They can still gain national recognition by more of a formal type of commercial. This way, you do not offend any particular race, and show that the vehicle is suitable for people of all ages, color, and race. Cadillac has become on of the mot powerful and influential car brand, that I feel they don’t need to do too much to market themselves. They already have a tremendously large market.

Friday, September 27, 2019

Is there a negotiation between NGOs and companies, or does it start Dissertation

Is there a negotiation between NGOs and companies, or does it start with a pressure - Dissertation Example Understanding the Firm-NGO alliances 25 2.7.5. Uneasy alliances: lessons learned from partnerships between businesses and NGOs in the context of CSR. 26 2.7.6. â€Å"Companies and NGOs- How Close is too close?† 27 2.7.7. The importance of governance structure in the B2N alliance 28 2.7.8. Equity 29 2.7.9. Alliance Contract 29 2.7.10. Equity Hostages 30 2.7.11. Negotiation 30 2.7.12. The Importance of Dialogue to the B2N Alliances 33 2.7.13. The importance of discourse and negotiations 35 2.8. Summary 39 Chapter Three: Methodology 3.1. Introduction 40 3.2. Hypotheses 41 Table 1. Research Questions and Hypotheses 42 3.3. Research Approach 43 3.4. Research Design 45 3.5. Research Strategy 47 3.6. Data Collection Method 47 3.7. Sampling 48 3.8. Procedure 49 3.9. Data Analysis 49 3.10. Summary 50 Chapter Four: Results 4.1. Introduction 51 4.2. Corporate Social Responsibility Initiatives 52 4.3. Corporate Social Responsibility Initiatives of Royal Dutch Shell and the Role of the NGO s 53 4.4. Corporate Social Responsibility Initiatives of British Petroleum and the Role of the NGOs 57 4.5. Corporate Social Responsibility Initiatives of Royal Bank of Scotland and the Role of the NGOs 59 4.6. Corporate Social Responsibility Initiatives of Barclay’s and the Role of the NGOs 60 Chapter 5: Discussions 62 Chapter 6: Conclusions and Recommendations 6.1. Conclusions 65 6.2. Recommendations 66 References 67 Chapter One: Introduction 1.1. Background of the Study Globalization has undeniably affected the people, the businesses and the entire world. Globalization is simply defined as the process by which the different states, markets, technologies and firms become integrated and interconnected (Baur, 2011; van Tulder, 2001). Evidently, globalization has become an... The intention of this study is globalization that has undeniably affected the people, the businesses and the entire world. Globalization is simply defined as the process by which the different states, markets, technologies and firms become integrated and interconnected. Evidently, globalization has become an important facet of the twenty-first century. One of the more specific effects of globalization is the increased levels of trade and foreign direct investments worldwide. Furthermore, globalization has also facilitated the interdependence of the different economies throughout the entire world. In addition to what has been previously mentioned, globalization has also influenced the development of Non-Governmental Organizations (NGOs) as a response to the recent increases in private investment. Non-Governmental Organizations consist of citizens’ groups that are organized on a local, national or international level. There are generally, three types of NGOs, these are: (1) advo cacy NGOs who are primarily tasked with the promotion of the governments or in international for the groups who do not have the capacity to do so; (2) operational NGOs, which primarily deals with the provision of goods and services to the clients who are in need; and lastly, (3) hybrid NGOs or those who perform both tasks previously mentioned. It is in this regard that NGOs are popularly known as those groups which are organized based on a certain issue. Most of the common objectives behind the establishment of the NGOs are the protection of human rights and that of the environment.

Thursday, September 26, 2019

The Basques Research Paper Example | Topics and Well Written Essays - 1500 words

The Basques - Research Paper Example With the incursion of the modern industrial age, however, in the form of mines and steel mills, much of the Basque tradition has disappeared along with its unique language, Catalan. Over the past thirty or so movements have arise to stop this progressive cultural deterioration and to restore the identity of the Basques—their language and culture—to former glory. These movements, however, suggest a separatist government apart of the central government of Spain, a demand fought violently by separatists groups that have to an extent damaged the Basque cause. The good position in which the Basques now find themselves can only maintained by denying the separatist movement as a radical tool of the past no longer necessary. The Basques: Background and History The homeland of the Basques, known by Basque nationalists as Euzkadi, lays claim to some of the oldest known people in Europe. Their land occupies the area on the French border near the Bay of Biscay and east to the area of San Sebastian. Although over the centuries overrun by scores of invading hordes from the south and east, the Basques remained until the tenth century â€Å"a fairly isolated† (Solsten and Meditz par 3) and distinct cultural group. Divided originally into two autonomous regions, the area was eventually absorbed by the powerful kingdom of Navarre. By the 16th century the kingdom became fragmented and war torn, and the Basque region was subsequently absorbed by the powerful lords of Castile--an event which even today raises the ire of true Basques who see themselves as separate in culture and language from the Castilian majority. Earlier Basque provinces were recognized as separate political entities with fueros, or full local privileges by the central governm ent of Castile and all went smoothly. But with the full centralization of the Spanish state and the protracted Carlist wars of the 1800s, the fueros were abolished, leaving the Basques and their culture at the mercy of various kings. Moves to reestablish the Basque region as autonomous from Castile in the 1930s were thwarted by the bloody Spanish Civil War of the 1930s. (Solsten and Meditz par 3) Worse for the Basques, with the victory of the Falangists over the Spanish Republican army, and the rise of Dictator Generalissimo Franco, the Basques became targets of Franco’s frenetic attempts to extinguish their language and culture and force them into the Spanish mainstream. With Franco’s death in the 1970s restrictions on the Basques and their culture were largely lifted, but feelings of absorption by the central Spanish regime remained an issue. For the Basques, their unsettled history from the mid-1900s onward has been one â€Å"clash† after the next with the â €Å"other Spain.† They resent the influx of heavy industrial activity—mines and steel mills—activity which brought a steady stream of non-Basque migrants to further dilute the language and culture. This steady decline of culture, while accepted by some, has been the root of serious violent disagreement over time between the Spanish government at large in Castile and hard core separatists in the form of the well-publicized terrorist activities of the ETA and its membership. The Basques: Politics Firstly, it is important to note that what constitutes being a Basque does not require residency in Spain or the Basque region. Many Basques, for a variety of reasons include those economic had left Spain over time and settled all over the world. As with other nationalities which have dispersed, there is a tendency to continue to identify with the group. This is sometimes true of the Basque, and sometimes not. In Belgium, for instance, there is a strong tendency to follow political

Union Management and Organization Essay Example | Topics and Well Written Essays - 1250 words

Union Management and Organization - Essay Example Union Management and Organization USA as country was growing due to rapid industrialization during 19th century as subsequently demand for labors was also growing at rapid pace. Historians named the phase as ‘Industrial Revolution† and as the frequency of inclusion of labors in the workforce increased subsequently the fear of insecurity from owners of the industry was automatically generated among workers. At that time, labors came across various examples of mistreatment such as physical abuse, extended work hours etc conducted by the owners of organizations and in such situation, they felt the urge of a protector group who can communicate the demand of labors to owners. As the time passed by, the protector group became the first organized union in USA. In 1837, the union of labors demanded to reduce the work hour and make it of less than 10 hours and finally organizations were compelled to grant the legislation of ten-hour workdays. After the success of first attempt to form organized labor union, small level city unions had organized and successfully established National Labor Union during 1866 (Murray, 2011). National Labor Union lobbied for Federal eight-hour workday but the demand was set for only government workers. At that time, two separate groups were also formed American Federation of Labor (AFL) and Knights of Labor in order to protect interest of workers. During late 19th century and early 20th century, valuation of unskilled labor pool in USA decreased due to the fact that owners of the organization had started to replace the unskilled workers by immigrants. As a result, unskilled workers in USA became vulnerable to low wages and poor working condition and these labors organized riots and strike in order to get their demands noticed (Murray, 2011). For example, strike by United Mine workers and Pullman Railroad workers in Pennsylvania were ended by Federal Government interventions. In many instances, AFL pressed Federal Congress to amend Union Labor Law and U.S. Departm ent of Labor was created in order to protect the rights and interest of wage earners. For example, Clayton Act was passed in 1914 in order to legalize boycotts and strikes. However, the situation had changed during Great Depression because during Great Depression, unemployment rate in USA significantly increased. At that time, legal act like Fair Labor Standards Act and Public Contracts Act were passed in order to address issues like child labor, overtime pay and minimum wage. Unionization had lost its wind during World War II and labor organization took no-strike policy at that time. After the War, Civil Rights Acts and Equal Pay Act were passed during 1960’s in order to address discrimination in workplace. After understanding the historical context of Union Labor Management, the essay will shed light on actions of unions and management to determine basic compliance with the major U.S. federal labor laws. According to draft published by U.S Department of Labor (2011), there should be an Administrator which will direct and supervise the actions of unions and management in the organization. According to the direction of Administrator, management and unions should appoint, select and classify labors in accordance to their merit. Unions should contact management regarding any discrimination in terms of wage, racial, working hour etc and both of them should take actions

Wednesday, September 25, 2019

The Essential Characteristics of Loving Assignment

The Essential Characteristics of Loving - Assignment Example According to Freud, present society is on the third level of restriction of sexuality: it controls even those sexual activities that are intended for procreation only (â€Å"Civilized’ Sexual Morality and Modern Nervousness† 6). This is dangerous, because in this situation: (1) individual libidinal characteristics (that often differ from the societal demands) are ignored and (2) every man and woman is being torn apart by 2 contradictory yet inescapable desires. One of them is the need of appreciation from fellow human beings, which is impossible when the sexual behavior of an individual is considered inappropriate. Another one is an instinct that Freud associates with love. In â€Å"Civilized’ Sexual Morality and Modern Nervousness†, the founder of psychoanalysis describes sexual instinct as almost a living creature that is innate in every human. It is a subject to development, and the problems in the way of this development lead to different types of neur oses (in the article, Freud distinguishes between neurasthenia and psychoneurosis (4). This â€Å"animal inside us† is incomparably greedy and cruel: it is â€Å"probably more strongly developed in man than in most of the higher animals; it is certainly more constant, since it has almost entirely overcome the periodicity belonging to it in animals† (â€Å"Civilized’ Sexual Morality and Modern Nervousness† 5). Freud does not recommend tolerating abstinence, as it suppresses the dangerous sexual instinct. In such cases, the latter is either ‘sublimated’ or resulting in neuroses. However, marriage does not offer any attractive alternatives, as it limits the sexual satisfaction of the couple to the pre-conception intercourses (â€Å"Civilized’ Sexual Morality and Modern Nervousness† 8). Following this logic, marriage is a severe stress, especially for women, so that neurotic girls cannot make the good party (according to Freud) and are succumbed to the abstinence-related neuroses (â€Å"Civilized’ Sexual Morality and Modern Nervousness† 8). In the paper â€Å"On the Universal Tendency to Debasement in the Sphere of Love†, Freud develops this theory of sexual instinct. As a physician, he approaches love technically, mainly as a working instrument of the explanation of neuroses: â€Å"The highest phase of development of which object-libido is capable is seen in the state of being in love, when the subject seems to give up his own personality in favor of an object-cathexis† (Freud, â€Å"On Narcissism† 76). From this quotation, it follows that sexual instinct is always object-directed, and it finds its objects either in the people surrounding an individual or an individual him/herself.  

Tuesday, September 24, 2019

A Shining Thread of Hope - The History of Black Women in America Essay

A Shining Thread of Hope - The History of Black Women in America - Essay Example It is through this strength and the resulting bonds of family, community and faith, the authors argue, that both yesterday’s and today’s African American woman is beginning to be recognized for her significant contributions to the progress and development of the United States and the importance she continues to play in providing examples to live, work and raise a family in trying times with dignity, grace, love and success. The prologue of the book immediately captures the reader’s attention with a detailed description of a young African woman’s life in the earliest days of the colonies. This pattern is continued with further detail into this and other stories of African women in the early colonies as the book moves into its first chapter. The sense of immediacy is developed as the authors fictionalize to a degree in describing Lucy Terry Prince and other early African women brought to America. â€Å"A young woman stood on the shores of the New World. †¦ We do not know this woman’s name, but we will call her Oni. She will be, for us, not a number – one of twenty slaves who were the first to be brought to North America – but the real woman she was† (8). Although they arrived on these shores as slaves, the authors demonstrate how these early slaves gained freedom, happiness, land ownership, scholarship and, at times, a degree of equality with their white nei ghbors. Yet there remain significant gaps to these stories as the children disappear or the family property is swallowed up by white invaders. â€Å"It is important to remember that other African Americans, women as well as men, were simultaneously creating a separate culture. Its development was not usually recorded, and few names have come down to us† (26). As they describe these stories, the authors also work to distance themselves from the stories, often switching back to the narrative scholastic voice of the present rather

Monday, September 23, 2019

Anishinaabe change maker Term Paper Example | Topics and Well Written Essays - 500 words

Anishinaabe change maker - Term Paper Example Much has been borrowed from her scholarly work as well as joint writing that reflect on her early life and personal contributions as an author and as a visionary politician. To bring or promote an acceptable positive change is a tasking accomplishment and contributions of Winona LaDuke cannot go unrecognized. She was brought up on a time when there was massive loss of land from her community a time in history when Ojibwa were reduced to inhabit reserves, which they only controlled about 10% of the land (Silverstone 91). The main factor influencing the need for a change was the immediate impacts related to land loss including unemployment and social problems such as poverty as well as the charge from her father who was an established activist on treaty rights and tribal issues (LaDuke 75). There was a dire need to re-establish the fading standards within the community and to ensure that they did not remain victims of land loss at any particular time. Winona LaDuke engagement in advanced studies and politics also influenced her role in championing for a change since this was the high time that she integrated with people social lives and learnt about their needs and existing community gaps. For instance, while undertaking her masters in community economic development LaDuke moved to White Earth where she was highly involved in local activities, which compounded her charge to engage in local tribal issues, and struggled to recover lands for Anishinaabe by practically all means possible (LaDuke 85). Her achievements are mainly embedded on the observable results and being an integral team player in instituting organizations which their central role was fighting for the well being of the marginalized or disadvantaged. As an activist LaDuke was an elemental team player in establishing and sustaining the Indigenous Women Network (1985), a center for affirmative action and social development that publicized forced sterilization and in turn activated a change for the

Sunday, September 22, 2019

Ethical Considerations for Teachers Essay Example for Free

Ethical Considerations for Teachers Essay Ethics and its essential considerations are fundamentals of human nature. Just like in any field of profession, the principles behind ethics are of undeniable significance to the educational setting. This is basically due to the concept that the teachers and the rest of teaching professionals are the ones who influence the thoughts, values and even conducts of the young ones. Such condition creates an enormous responsibility for teachers to ideally shape the future members of the society hence it is expected of them to correctly practice what they teach or preach. Beyond the theories, ethical considerations are of utmost importance in the performance of the teaching profession. It is essential to carry out ethical ideas in manners that are practically acceptable to human attributes. Teachers are required to impart moral principles to their students. However, it will always be the educators’ innate characters and individual behavior which spell the difference in eventually producing respected or morally upright persons. In order to come up with an ideal educational system, therefore, it is vital not to just adhere but also live up to necessary ethical considerations. In an educational setting, members of the learning organization particularly teachers are supposed follow or exercise specific ethical considerations. This is because there is a constant struggle between a teacher’s personal interest and professional commitment. Citing May (1990), this situation was emphasized by Smith (1996) who said that teachers are always susceptible to their respective concern as well as dedication to live up and maintain the dignity of the academic field. In effect, such conflicts have resulted into relevant ethical dilemmas that have inevitable implications to other learning professionals, the students and one’s mandate to the teaching career (Smith, 1996). In order to address, if not resolve the issue, Smith mentioned the suggestions made by May. That is, there is a need to recognize and even reiterate significant ethical considerations which teachers are responsible of. These include the sincere manifestation of respect for any colleague or student as an individual. Truthful communication and encouraging others’ confidence are also the needed ethical considerations. Most importantly, it is fundamental for teachers to help create just and caring cultural and social structures that uphold the benefit of all people within the educational organization (Smith, 1996). To carry out such ethical considerations, teachers are also required to perform several standards of professional communication. It is required for teachers to help their respective organizations to achieve their academic goals. Educators also need to exert additional efforts for the respective professional and individual enhancements of their colleagues and students. The ethical consideration of professional interaction likewise calls for teachers’ kindness as well as comprehensive and reasonable evaluation of functions of students and co-teachers. Lastly, teachers need to perform their roles in manners that support and even exceed the principles of ethical considerations (Smith, 1996). When the said ethical considerations are incorporated on existing educational policies, students will be completely empowered and provided with ideal instructional materials thus preventing teachers from providing documents outside the required curriculum. Students will also be assured of a teacher’s presence resulting to better education. The carrying out of examinations and making of grades will happen in ways beneficial both to teachers and students. In doing all these considerations, the educational setting is sure to exemplify a successful professional condition and effective relationship between teachers and students (Smith, 1996). Similar to any other professions, ethical considerations are of extreme relevance to the educational environment. Therefore, it is empirical to realize the individual behavior of teachers. This is due to the underlying principle that what teachers do and how such activities are performed are sure to ultimately affect all the people within the educational setting. Reference Smith, R. M. (1996). Essential ethical considerations in education. Retrieved February 6, 2009, from http://findarticles. com/p/articles/mi_qa3673/is_n1_v117/ai_n28677142/pg_4? tag=content;col1

Saturday, September 21, 2019

Biological Significance of BST2 Overexpression in OSCC

Biological Significance of BST2 Overexpression in OSCC Overexpression of BST2 is associated with nodal metastasis and poorer prognosis in oral cavity cancer ABSTRACT Objective: Bone marrow stromal cell antigen 2 (BST2) was one of the proteins which were found related to tumor metastasis in our previous proteomic study. Now we want to examine its clinical role on the oral cavity squamous cell carcinomas (OSCC). Study Design: Individual retrospective cohort study and basic research. Methods: Immunohistochemical analysis, Western blotting, and quantitative real-time polymerase chain reaction were used to demonstrate the expression levels of BST2 on 159 OSCC tumors. RNA interference was utilized for cell migration and proliferation study in vitro. Results: BST2 expression was significantly higher in OSCC cells of metastatic lymph nodes and primary tumor cells, compared to adjacent normal epithelia. Higher BST2 expression was associated with positive N stage, advanced overall stage, perineural invasion, and tumor depth (P = 0.049, 0.015, 0.021, and 0.010, respectively). OSCC patients with higher BST2 expression had poorer prognosis for disease-specific and disease-free survival (P = 0.009 and 0.001, respectively). Multivariate analyses also demonstrated that higher BST2 expression is an independent prognostic factor of disease-specific and disease-free survival (P = 0.047 and 0.013, respectively). In-vitro suppression of BST2 expression in OEC-M1 cells showed that BST2 contributes to tumor migration of OSCC cells. Conclusions: The findings in this study indicate that BST2 expression in OSCC tumors is an independent prognostic factor of patient survival and associated with tumor metastasis. Keywords: oral cancer; head and neck; BST2; metastasis; OSCC; tumor marker; squamous cell carcinoma. Level of evidence: NA Introduction Oral cavity squamous cell carcinoma (OSCC) is the most common head-and-neck cancer worldwide and remains a difficult malignancy to treat because of approximate 50% mortality rates in spite of recent advances in the contemporary management over the past three decades.1-4 Cervical lymph node dissemination has been long regarded as one of the major poor prognosticators in patient with OSCC and is a major obstacle to OSCC management. 5-8 Previously, some transcriptomic studies analyzing OSCC tumors have established the expression signatures of OSCC metastasis.9-13 On the other hand, our group also used a proteomic approach by isobaric tags for relative and absolute quantitation to identify proteins that are differentially expressed between laser capture microdissected primary and metastatic OSCC tumors and some potential markers of OSCC metastasis were therefore discovered.14 From the candidate proteins derived from by this approach, bone marrow stromal cell antigen 2 (BST2) was identifi ed as one of the potential molecules associated with OSCC metastasis and need further validation in the clinical scenario.14 The BST2 gene is located on chromosome 19p13.2 and codes for a 35kDa transmembrane glycoprotein consisting 180 amino acids. It is also known as the HM1.24 antigen, CD317, and tetherin.15,16 BST2 has been found to be expressed on mature B cells but not on other normal tissues of health individuals.15 The BST2 overexpression has been identified in several cancer types such as multiple myeloma, endometrial cancer, gastric cancer, and glioblastoma multiforme.17-23 Moreover, BST2 was discovered associated with the tumor progression and metastasis by previous findings from the pancreatic endocrine tumors with liver metastases and the breast cancers with bone metastasis.24,25 In vitro, overexpression of BST2 increased invasion, migration, cell proliferation and apoptosis evasion in breast cancer cells.26,27 Thus, based on the findings of these previous studies and our proteomic discovery, we also hypothesized that BST2 is overexpressed in OSCC and plays a specific role in tumor cell modulat ion. Accordingly, our study is designed to investigate the expression and the role of BST2 in the OSCC tumors. Immunohistochemical analysis and quantitative real-time PCR were used to demonstrate the expression levels of BST2 on OSCC tumors. We also employed RNAi techniques to suppress the BST2 expression to investigate the effects of BST2 modulation on the OSCC cell line in vitro. Materials and Methods Patient Characteristics and Clinical Specimens One houndred and thirty-eight male and 21 female were diagnosed as OSCC patients at the Chang Gung Memorial Hospital (Tao-Yuan, Taiwan) between 2002 and 2007 and enrolled in this study. Patient age at diagnosis ranged from 22.0 to 84.0 years (mean, 51.9 ±12.3). The associated subsites of the oral cavity were buccal mucosa (62 patients), gum (21), hard palate (5), lip (5), floor of the mouth (5), and tongue (61). Patients with at least one of the following conditions were considered ineligible: unresectable or inoperable cancer, other primary cancer (synchronous or metachronous), recurrent cancer, distant metastasis, prior history of malignancy, treatment with neoadjuvant therapy, medical contraindication for surgery, or individuals lost to follow-up. Lesions diagnosed as carcinoma in situ, verrucous carcinoma or a histologically basaloid subtype were also not included in the study. All patients provided informed consent prior to study participation, and the study was approved by th e Institutional Review Board of Chang Gung Memorial Hospital. Patients underwent standard preoperative work-ups according to institutional guidelines, including detailed medical history, complete physical examination, computed tomography or magnetic resonance imaging scans of the head and neck, chest radiographs, bone scan, and abdominal ultrasound. Primary tumors were excised with adequate margins under intraoperative frozen section control. Surgical defects were immediately reconstructed via free flap or local flap by plastic surgeons, if necessary. Following surgical treatment, pathological TNM classification of all tumors was established according to the American Joint Committee on Cancer Staging Manual (2007). After discharge, all patients had regular follow-up visits every 2 months for the first year, every 3 months for the second year, and every 6 months thereafter.28-30 RNA Extraction and Quantitative Real-time RT-PCR Detection of BST2 According to the manufacturer’s protocol, total RNA of sixty paired OSCC tumor and adjacent normal tissues was extracted and purification by using RNAzol B reagent (Tel-Test, Friendwood, TX) and an RNeasy cleanup kit (Qiagen, Valencia, CA). 5ug of total RNA was used for first-strand cDNA synthesis and then adding to a reaction mixture comprising of commercially purchasable primers (BST2 Hs00171632_m1 and normalization control B2M, Hs00984230_m1 and ACTB, Hs99999903_m1 ; Assay-on-Demand, Applied Biosystems, Foster City, CA), TaqMan Universal PCR Master Mix, and RNase-free water. 7900 HT Sequence Detection System was used for performing quantitative real-time RT-PCR and the result was analyzed with SDS version 2 (Applied Biosystems, Foster City, CA). All experiments were repeated in duplicate, and the mean fold-change of each sample was calculated. Western blot analysis Proteins were extracted from culture cells with RIPA buffer (50 mM Tris pH 8, 0.0150 mM NaCl, 2 mM EDTA, 1% Triton X-100, 0.1% SDS, 0.2 % Na-deoxylate, 1x protease cocktail (Sigma-Aldrich, St. Louis, MO), and the concentrations determined using the BCA protein assay kit (Perice Biotechnology) Samples were separated on 12% SDS gels, transferred to PVDF membranes (GE Healthcare Life Sciences, Buckinghamshire, UK), and probed using rabbit monoclonal anti-BST2 antibody (Epitomics, Burlingame, CA), mouse monoclonal beta-actin antibody (MAB1501, Chemicon, Billerica, MA), and mouse monoclonal GAPDH antibody (Novus, Littleton, CO). The beta-actin and GAPDH signals were used as the loading controls. Densitometer quantitation was also measured to demonstrate the relative fold differences of prtein levels. Enzyme-linked immunosorbent assay (ELISA) measurement ELISA kit for human BST2 (CUSABIO, Hubei, China) was used for determining the BST2 levels in the tested samples. Human recombinant BST2 was used as the standard. Briefly, 100 ÃŽ ¼l of samples or standard were added to a murine monoclonal antibody against BST2 coated microtiter plates and incubated for 2 h at room temperature. After the plates were washing with wash butter for three times, a biotin-conjugated polyclonal antibody was added and further incubated for 1 h at room temperature. The plates were washed three times again and 100 ÃŽ ¼l of horseradish peroxidase-avidin was added at room temperature for 1 h. After the plates were washed five times and 90 ÃŽ ¼l of tetramethylbenzidine was added to each well. The reaction was terminated by adding of 2 N sulfuric acid, and the optical density of each well was measured by a microplate reader set to 450 nm. Each experiment was performed in triplicate. Immunohistochemical Staining For immunohistochemistry, formalin-fixed and paraffin-embedded tissues were cut into 4 à ¯Ã‚ Ã‚ ­m sections, deparaffinized, rehydrated, and prepared for antigen retrieval. Slides of consecutive sections were incubated with the appropriate antibodies: rabbit monoclonal anti-BST2 antibody (diluted 1:30, Epitomics, Burlingame, CA) at room temperature for 1 hour. After incubation, slides were washed three times with phosphate buffered saline, incubated with horseradish peroxidase polymer antibody (Invitrogen, Carlsbad, CA) at room temperature for 10 min, and developed by the addition of 3,3’-Diaminobenzidine tetrahydrochloride (DAB) reagent (Dako, Glostrup, Denmark) as the chromogen and hematoxylin as the counterstain. A ScanScope CT automated slide-scanning system (Aperio Technologies, Vista, CA) was used for obtaining images of stained slides. Expression of BST2 was scored using a combined scoring method accounting for both percentage of stained cell s and staining intensity and.31-33 Strong to negative staining intensities were scored from 3 to 0. For each intensity score, cells staining at that specific level were visually estimated and calculated as a percentage. The resultant combined score was calculated as the sum of the intensity scores multiplied by the percentage of stained cells. All specimens were evaluated independently by our pathologists (Liang Y and Hseuh C) who had blinded to clinical origin of the specimen. Knockdown of BST2 Using RNA Interference (RNAi) SMARTpool small interfering RNAs (siRNA) were purchased from Thermo Scientific (Dharmacon, Lafayette, CO) .RNAi specifically targeting human BST2 (No. L-011817-00-0005, Dharmacon) and a scrambled control RNAi (No. D-001810-10-05, Dharmacon) were purchased from Thermo Fisher Scientific (Rockford, IL). RNAi (at a final concentration 400 nM) was mixed with Lipofectamine RNAiMAXTM (Invitrogen, Carlsbad, CA) and Opti-MEM medium (Invitrogen, Carlsbad, CA) without serum, incubated for 20 min at room temperature, and then added to OEC-M1 cells that were seeded at a density of 1 Ãâ€" 105 cells per well in six-well plates. After incubation for 6 h at 37 °C, transfer fresh culture medium (RPMI medium containing 10% FBS) was added to each well. After transfection for 48 h, cells were harvested for analysis of cell migration, and invasive capacity. Cell Proliferation Assay Cell proliferation ability was determined using the methylthiazoltetrazolium (MTT) assay (Bionovas Biotechnology, Toronto, Canada). After transfection for 24 h, cells were seeded at a density of 5 x103cells/well in RPMI medium containing 10% FBS. At the end of another 48-hour incubation period, the medium was exchanged with MTT solution at a final concentration of 1 mg/mL, and cells placed in a culture incubator at 37oC for 1 h. After washing twice with PBS, cells were solubilized with 0.1 ml of DMSO at 37oC for 1 h. The converted dye was measured at 540 nm. Three independent experiments were performed in quadruplicate. The average value of the control experiment was taken as 100% proliferation, and used to calculate the percentage of cell proliferation for each treatment. Cell Migration Assay Cell migration was evaluated using a chemotaxis chamber (Corning, Lowell, MA) with a polycarbonate membrane (8-ÃŽ ¼m pore size) placed between the two chambers. Transfected OEC-M1 cells (1 Ãâ€" 105) in 200 ÃŽ ¼l of serum free culture medium were applied to the upper chamber and 600 ÃŽ ¼l of RPMI medium containing 10% FBS medium was added to the lower chamber. Chambers were incubated at 37 °C for 16 h, and then the membrane was fixed with methanol for 10 min and then stained with GIEMSA (Sigma-Aldrich, St. Louis, MO). Cotton swab was used for removing the cells on the upper surface of the filter, and the cells which migrated through the membrane were counted in eight different visual fields under a light microscope (magnification: 200x). Each migration assay was performed in triplicate during three independent experiments. Statistical Analysis All statistical data display as means  ± SD. The significance was examined by Wilcoxon test. The Wilcoxon signed ranks test was employed for comparison of the relative signal intensity of quantitative real-time RT-PCR and immunohistochemical staining scores between paired tumor and pericancerous normal mucosa samples. All patients had regular follow-up evaluations at our department until Apr 2012 or death. Survival analysis was plotted using the Kaplan-Meier method, and differences evaluated using the log-rank test. The specific risk factors for disease-specific survival were analyzed with multivariate regression. Statistical analyses were performed using SAS software (version 9.1; SAS institute, Cary, NC). All P values were two-sided, and statistical significance accepted at P Results Overexpression of BST2 in tumor cells of OSCC tissues. Expression of BST2 was examined by quantitative real-time RT-PCR in 60 paired OSCC tumor and adjacent normal tissues. Transcripts for BST2 were significantly elevated in OSCC tumor specimens as compared with adjacent normal tissue (155  ± 205 vs. 38  ± 53, P PP= 0.533; Fig. 1B), indicating that BST2 is more highly expressed in tumor cells of metastatic lymph nodes and primary tumor cells and almost absent in normal oral epithelia. Association of BST2 expression with various clinicopathological manifestations Next, we evaluated the relationships between increased BST2 expression and various clinicopathological characteristics of OSCC patients (Table 1). Higher BST2 expression was significantly associated with higher pN status, advanced overall stage, positive perineural invasion, and greater tumor depth (P=0.049, 0.015, 0.021, and 0.010, respectively; Table 1). However, we observed no association between BST2 overexpression in OSCC tumors and patient age, sex, T stage, differentiation or bone invasion. Consistent with our hypothesis, BST2 overexpression was significantly (P=0.049) associated with nodal metastasis (pN status). Association of BST2 expression with overall survival (OS), disease-specific survival (DSS), and disease-free survival (DFS) Based on expression data obtained from IHC, patients were stratified into two groups (high vs. low expression using 160 out of 300 as the cut-off value), and the possible association of BST2 expression with patient OS evaluated. Survival analysis revealed that the five-year OS rates for patients stratified into high and low BST2 expression subgroups were 66.8% and 51.2%, respectively. These differences in OS were not significant, compared in the log-rank test (P=0.059; Figure 2A). However, the Kaplan-Meier plots evaluated 5-year DSS rates for patients stratified by high and low BST2 expression as 74.0% and 53.7%, respectively. These differences in DSS were statistically significant, as observed with the log-rank test (P= 0.009; Figure 2B). Moreover, five-year DFS rates for patients stratified based on high or low BST2 expression were also significantly different in the log-rank test (75.9% and 51.2%, respectively; P= 0.001) (Figure 2C). BST2 expression was additionally a significant predictor of DFS and DSS in univariate analysis with the Cox proportional regression model. To further ascertain whether BST2 expression can be applied as an independent predictor of patient survival, multivariate analysis was performed using age, gender, pT status, pN status, overall stage, perineural invasion, tumor differentiation and BST2 expression as parameters in the Cox proportional regression model. Our results indicated that pT status, pN status and BST2 expression are independent predictors of DSS (P= 0.017, 0.002, and 0.047, respectively; Table 2). Similarly, we also found that pT status, pN status and BST2 expression are independent predictors of DFS (P= 0.014, BST2 Promotes OSCC Cell Migration In Vitro To evaluate the biological significance of BST2 overexpression in OSCC using an in vitro system, endogenous expression of BST2 in OSCC cells was knocked down using gene specific RNAi. The effects of RNAi were determined by the ELISA method in the supernatants of OEC-M1 cells transfected with either BST2-specific RNAi (si-BST2) or a scrambled sequence control RNAi. As shown in Supplementary Figure 2A, the levels of endogenous BST2 was significantly reduced (P=0.003; Supplementary Figure 2A) in si-BST2–transfected cells as compared with cells transfected with the control RNAi. Control and si-BST2–transfected cells were further analyzed for cell proliferation and migration. As shown in Supplementary Figure 2B, the cell proliferation ability in OEC-M1 cells was not significantly decreased in the si-BST2–transfected cells compared to the control RNAi transfected cells (P =0.435; Supplementary Fig 2B). However, the capability of OEC-M1 cell migration attenuated by addi tion of si-BST2 (70.2% reduction, P = 0.001; Supplementary Figure 2C). Collectively, these findings indicated that overexpression of BST2 in vitro can mediate cell migration in OSCC cells.

Friday, September 20, 2019

Company Profile of Lactalis

Company Profile of Lactalis I HISTORY         Ã‚   Lactalis is a family-owned company based in Laval, Mayenne, in France. Andrà © Besnier started his cheese maker activity in 1933. It started with the name of Socià ©tà © Besnier when Andrà © Besnier collected 35 liters of milk and made 17 camemberts out of it. Since then, the company changed its name to Lactalis in 1999 and became the world leader of dairy products. Chronology Some key Dates 1933  Andrà © Besnier establishes a cheese making business 1968  Besnier creates the Prà ©sident brand 1977  Michel Besnier launches products abroad and creates the service Besnier Export 1980  The group becomes the 1st European dairy company 1986  Besnier Export becomes Besnier International 1999  The company changes its name to Groupe Lactalis 1999  Besnier International becomes Lactalis International 2005 Lactalis purchased A. McLelland and Son Limited, a Scottish based cheese manufacturer 2006  Buyout of Galbani, leader of cheese in Italy and Italian cheeses in Europe. Lactalis becomes the 2nd cheese leader worldwide. 2006 Joint venture between the Lactalis Group and Nestlà © 2010  Acquisition of Puleva in Spain, 2nd leader for milk in the country. 2010 Acquisition of; Rachels Dairy Limited, the 2nd for organic yogurts and 1st for organic flavoured big pot yogurts in the UK 2011  Acquisition of Parmalat, Italian dairy company. Lactalis becomes the 1st; dairy company in the world II COMPANY STRUCTURE AND ORGANIZATION Lactalis is a private company owned by the Besnier family, with Emmanuel Besnier, the founders grandson, as its CEO. The company employs around 75 000 people. Lactalis owns 230 industrial sites in 43 countries.Lactalis is the: à ¯Ã†â€™Ã‚   1st dairy company worldwide 1st cheese making company worldwide 1st milk collecting company in Europe 1st cheese maker in Europe The commercialization of products in Asia, Africa, Oceania, the Middle-East and in DOM-TOMs (French overseas departments and territories) is managed by Lactalis International. Divisions in Lactalis Group Lactalis cheeses Lactalis Butter Creams Lactel Lactalis AOC Lactalis consumption AFH Lactalis industry Lactalis International LNUF Lactalis feed Job sectors Procurement Milk collection Sales Finance finance controlling Industrial Information technology Legal department Supply chain Marketing Quality Research and development Human resources III AREAS OF OPERATION Industrial presence worldwide Location of offices and subsidiaries worldwide Red Subsidiaries/ Offices : Lactalis CaraÃÆ' ¯bes; Lactalis Indian Ocean; Algeria; Egypt; Saudi Arabia; Gulf CC and levant; Lactalis Japan; Lactalis China; Lactalis Hong Kong; Lactalis Vietnam; Lactalis Singapore;;;;;;;;;;;;; Grey Export Lactalis International : Sub-saharan Africa; Maghreb-Mediterranean; Rest of Asia; Pacific Blue Other: Lactalis American Group; Lactalis Europe; Lactalis Europe de lEst; Lactalis CEI; Lactalis Australia IV PRODUCTS Product Mix Lactalis Groups product mix and product lines are wide: cheese, yoghurt, milk, cream, butter, powder milk, milk drinks, milk replacers, etc. Lactalis owns a lot of prestigious brands, in France and in other places in the world. Some brands and products Cheese : Prà ©sident Rouy Lepetit Bridà ©light Galbani Rondelà © Munsters Little Friends Butter and creams : Prà ©sident Bridà ©lice Bridà ©light Primrose Galbani Milk : Lactel -; Prà ©sident Ultra-fresh : Nestlà © Nutrition : Cà ©lia Milk replacers : Lactapro Eurovo Manufacturing process Lactalis Group takes the greatest care in collecting the best milk in France and in the world. The development of the Lactalis Group has always been done in respect of human beings and in respect of their partnership with milk producers. In France and abroad, Lactalis Groups constant investments in industrial development and innovation are an insurance of the optimization of milk production. Milk collection Several conditions are necessary to guarantee the production of milk in quantity and in quality: favorable climate, availability of water, extensive agricultural areas, good diets, and technical skills. Lactalis Group has been able to draw the full potential of its dairy tradition and is now the worlds third largest milk collector with more than 18 billion litres collected annually (5.6 billion in France) and is also working in the sheep and goat milk sectors. Environment More than fifty technicians and salespeople of the Group are in contact with milk producers to provide advice and technical assistance. This ensures milk quality, respect for the environment and animal welfare. Lactalis is committed to the environment with the adoption of a charter called Cap sur lavenir (Heading for the future). This commits the firm to good animal husbandry practices, respecting animal welfare; but also to better environmental practices and the limitation of greenhouse gas emissions. Lactalis also deploys energy diagnostics producers to improve its facilities, limit gas emissions, control the temperature of heating, or improve other parameters in order to save energy, such as installing pre-coolers for milk or heat recovery units. Organic milk Lactalis has been involved in organic production for more than 20 years. With the growth of the organic market, products are more and more diverse: UHT milk, cream and butter. Lactalis became the leader in the market of organic milk with their brand Lactel. The collection of organic milk is of 135 million litres of milk, which represents 2.5% of the groups collection. Over the last five years, Lactalis has been accompanying 265 dairy farms engaged in a process of organic conversion. Cows diet Lactalis is in partnership with Valorex to help producers to optimize the feeding of cows and thus improve the quality and properties of the milk produced. The composition of the cows diet contains less soy, more grass, flax, clover, peasà ¢Ã¢â€š ¬Ã‚ ¦ This change in diet results in more than 500 less tones of imported soybeans, almost 500 new hectares of flax. (Flax seeds are rich in Omega 3 and antioxidants), 400 new hectares of grass and alfalfa, and 156 hectares of peas, fababeans, rapeseed, and lupine. This gives an enriched milk of Omega 3, with less saturated fat. It also impacts the cows metabolism and the number of tons of CO2 produced by their digestion is also reduced. V STRATEGY Lactalis strategy is about professionalism, which can be seen in its wide range of products, as in its will to give the best quality of products to its consumers.;;;;;;;;;;;;; They also support their brands abroad by organizing several marketing and commercial actions. Diversification Their main strategy is diversification. They already have a wide range of different dairy products, owning a big share of the market. Their diversification is based on large-scale milk processing in all its forms, placing stress on quality production. They aim for better breeding practices, a certification of producers, a monitoring of milk quality and sustainability. Expansion strategy Another main point of their strategy is market expansion. Buyout of other companies is their way to reach more markets and consumers locally and worldwide. They entered the ultra-fresh market by doing a joint venture with Nestlà ©, called Lactalis Nestlà © Produits Frais LNPF, owned 60 % by Lactalis. They made the acquisition of Puleva and Forlasa in 2010, which have a dominant position in Spain. They also acquired Galbani in 2006, Italys first cheese producer, and Parmalat in 2011. These are only some examples of Lactalis expansion. V FINANCIAL STRUCTURE Capital structure of Lactalis The capital structure of Lactalis shows that the Besnier family owns 100% of the firm. Emmanuel Besnier, its CEO, is the majority shareholder. Capital Structure of Lactalis, propriety of the Besnier family Turnover of the company and its distribution Financial data by year Year 2004 2005 2008 Turnover  £5.6 billion (25% abroad)  £6 billion (40% abroad)  £9.35 billion Year 2009 2010 2016 Turnover  £8.5 billion (56% abroad)  £14.7 billion (74% abroad)  £17 billion Prà ©sident is sold in 160 countries and produces more than  £1.8 billion turnover. Galbani is sold in 140 countries and produces more than  £1.5 billion turnover.      Ã‚   VI PROGRAMMES TO ATTRACT YOUNG GRADUATES The Commercial and Marketing Graduate programme allows young graduates to work as a Product Manager or Sector Manager. The Maintenance programme allows to work at several of their production sites to develop potential and broaden knowledge. The Finance controlling programme offers a 6-month internship, followed by a 24-month international internship (V.I.E). The Industrial programme is designed to transfer French dairy expertise to foreign students. It is a sandwich course programme at the Higher School of Agriculture in Angers (ESA), combining periods at school with work experience in two production sites in France with an offer of work placement after two years. REFERENCES Agro, L. (2017). Lactalis : le PDG Emmanuel Besnier en est lactionnaire majoritaire Lusine Agro. [online] usinenouvelle.com/. Available at: http://www.usinenouvelle.com/article/lactalis-le-pdg-emmanuel-besnier-en-est-l-actionnaire-majoritaire.N151974 [Accessed 21 Mar. 2017]. Anon, (2017). [online] Available at: http://www.iuf.org/sites/cms.iuf.org/files/The%20Lactalis%20Group.pdf [Accessed 21 Mar. 2017]. Groupelactalis.co.uk. (2017). Groupe Lactalis UK. [online] Available at: http://groupelactalis.co.uk/ [Accessed 21 Mar. 2017]. En.wikipedia.org. (2017). Lactalis. [online] Available at: https://en.wikipedia.org/wiki/Lactalis [Accessed 21 Mar. 2017]. Fr.wikipedia.org. (2017). Lactalis. [online] Available at: https://fr.wikipedia.org/wiki/Lactalis [Accessed 21 Mar. 2017]. Lactalisfeed.fr. (2017). Lactalis Feed | Lenfance de là ©levage. [online] Available at: http://www.lactalisfeed.fr/en/ [Accessed 21 Mar. 2017]. Lactalis-international.com. (2017). Lactalis international Accueil. [online] Available at: http://www.lactalis-international.com/ [Accessed 21 Mar. 2017]. Lactalis. (2017). Le Groupe Lactalis Lactalis. [online] Available at: http://www.lactalis.fr/ [Accessed 21 Mar. 2017].

Thursday, September 19, 2019

A Worn Path Essay -- essays research papers

In the modern short story, Eudora Welty clearly develops Phoenix Jackson as a main character who indirectly manipulates other people. Phoenix, as the speaker in â€Å"A Worn Path† holds the status of an old Negro woman who continues the everyday cycle of life. Although, in reality Phoenix is an average human being, who feels she must be rewarded for living. Phoenix believes that humanity owes her something for the troubles she encounters throughout her lifetime. When Phoenix says to the hunter, â€Å"that’s as far as I walk when I come out myself, and I get something for my trouble† (paragraph 46). Incidentally, Phoenix replies to the old hunter’s question it is quite clear that she undoubtedly is expecting compensation; whether it is a pity party or a monetary gift to settle the score. Because Phoenix feels like she must abuse other people, she appears to have the power to be in control of any situation that might come her way. Throughout Welty’s â€Å"A Worn Path,† Phoenix Jackson and her actions symbolize her to be a selfish and manipulative woman. Phoenix’s obsession with power, is the basis of her idea to manipulate other people; which is clearly explained through her dialogue with the persons she comes in contact with on her journey into town. Along with Phoenix’s obsession with being pitied upon by the hunter, she also feels like she never plans to succumb to defeat. When Phoenix replies to the old man’s question concerning why she was laying in the bushes; she said, â€Å" Lying on my ...

Wednesday, September 18, 2019

The Author to Her Book by Anne Bradstreet Essay -- The Author to Her B

â€Å"The Author to Her Book† by Anne Bradstreet In â€Å"The Author to Her Book,† Bradstreet is inundated in indecision and internal struggles over the virtues and shortfalls of her abilities and the book that she produced. As human beings we associate and sympathize with each other through similar experiences. It is difficult to sympathize with someone when you don’t know where they are coming from and don’t know what they are dealing with. Similar experiences and common bonds are what allow us to extend our sincere appreciation and understanding for another human being’s situation. In this poem an elaborate struggle between pride and shame manifests itself through an extended metaphor in which she equates her book to her own child. "The Author to Her Book" expresses some of the emotions Bradstreet felt when her most intimate thoughts were made know to the world with the publishing of her book. In addition she also relates some of the story as to how her work came to be published. The average person could not relate to the distress Bradstreet feels in this situation. The collection of poetry that she had written expressed her feelings in a way that most women during that time didn’t have the skill to do. Many people would wonder why Bradstreet the publishing of her work would be so distressful when they had brought Bradstreet much personal fame and brought many people enjoyable reading. Therefore, she could not simply write a clear-cut poem to tell how she feels about her stolen thoughts. Only another writer would be able sympathize with Bradstreet in this matter if she didn’t draw some basis for comparison. In order for her readers to be able to feel her pain and joy she had to use a situation in which her readers could comprehend the many emotions she experienced. Many of the women who read her poetry were either already mothers or would one day be mothers. This common bond opened a door for understanding. By comparing her book to a child, she is able to gain the compassion of her readers and help them appreciate the emotions she is feeling. In line one she states how she feels about her creation, which she calls an "ill-formed offspring" (line 1) and she gives the book human characteristics throughout the poem to enhance the effect of the conceit. She constantly speaks directly to her work as if it were her own child. Then in line 23 Bradstreet calls hers... ...nyone to read. But was with Bradstreet I stood behind my work even though it may not have been perfect and I think every writer could relate to here situation. Most people could not so the metaphor she used out in perspective for those who are not writers. In a small sense this poem lets the reader gaze into Bradstreet’s nature and our own. This poem along with all the other she wrote was a way for her to express her emotions into words, in this case about something very specific. As a columnist I can appreciate what she is doing and I understand the feeling she was trying to convey about the judgment she was sure to receive from the publishing of here work. Through her use of this extended metaphor, Bradstreet weaves a brilliantly intricate web of parallels: Parent and author, child and book, creator to creation. These parallels allow the reader to emotionally relate and sympathize with Bradstreet. She succeeds in conveys here feeling and giving the reader a means of association with what she is feeling. She used the pain and pleasure of creating and nurturing human life to show people who were not writer the pains and the pleasures of have your work exposed to the world.

Tuesday, September 17, 2019

Genetically Modified Foods Essay

Genetically modified foods have recently been in the new headlines for both their positive attributes and the negatives of genetic modification, this essay will look at the effects Genetically Modified foods have on the economy, environment and you. Genetically modified (GM) foods refer to crop plants which have been created for human or animal consumption, these foods have had their genetic material modified in a way that would not occur naturally within the food. Desired traits such as increased resistance to herbicides or improved nutritional content are some ways food can and have been genetically modified. Traditionally, modifying plant to have a desired trait has been undertaken through breeding, conventional plant breeding methods are time consuming and are often inaccurate. (Better Health Channel, 2013) Genetic modification can create crops with the specific traits rapidly and accuracy. For example, the gene responsible for drought tolerance can be inserted into a different plant species, the GM plant will become drought tolerance as well as the host plant previously was. Experts say 60% to 70% of processed foods on Australian shelves have genetically modified ingredients. The most common genetically modified foods are soybeans, maize, cotton, and rapeseed oil. That means many foods made in Australia containing corn or high-fructose corn syrup, such as breakfast cereals, and snack foods, these ingredients appear frequently in animal feed as well. Today’s techniques of genetic modification provide innovative and infinite of improving specific traits in different crops. For example, physical means of removing weeds is time and cost consuming for farmers, they will often spray their crops with a variety of herbicides to destroy the weeds, this process takes great care to ensure the crop isn’t affected by the herbicide, GM plants modified to be resistant to a variety of herbicides could prevent damage to the environment by reducing the amount of herbicides required. Monsanto has created a strain of soybeans genetically modified to be not affected by their herbicide product Roundup. A farmer grows these soybeans which then only require one application of weed-killer instead of multiple applications, reducing production cost and limiting the dangers of agricultural waste run-off. (Kartha, 2013) Third world counties where malnutrition is major issue, could benefit greatly from GM crops. Impoverished people in Africa and Asia rely on a single staple crop such as rice for the majority of their diet. Rice, however is not an adequate staple with the correct amount of vitamins and nutrients to fully nourish a human. If rice where to be genetically modified with additional vitamins and minerals, malnutrition wouldn’t be an issue for third world countries. (Csa. com, 2013) As this issue grew it became a concern for Professor Ingo Potrykus and Peter Beyerin who created The Golden Rice project, Potrykus and Beyerin in a collaborative effort were able to show that production of ? -carotene could be turned on in rice grains using Genetic Modification, Potrykus enabled golden rice to be distributed free to subsistence farmers. Free licenses for developing countries were granted quickly due to the positive publicity that golden rice received. Golden rice was said to be the first Genetically Modified crop that was unarguably beneficial. (Mayer, 2013) Environmental activists, professional associations and other officials have all raised concerns about Genetically Modified foods, and criticized laboratories for pursuing profit without concern for potential hazards to humans and the environment. Genetically Modified foods have a long list of benefits, but along with the positive comes the negative, one concern for Genetically Modified foods is increased toxicity, most of the flora that is consumed by humans produce low level toxins, low enough that they don’t cause any adverse health effects. The concern is that inserting an exotic gene into a crop plant may cause its toxicity levels to rise significantly due to the new gene casing the host plant to stress and produce toxins as a defense or altering the plants toxin producing cells completely causing it to produce toxins at a rate dangerous to human health. Although these effects have not been observed in Genetically Modified crop plants, they have been observed through conventional breeding methods, causing scientist to become concerned with the safety of Genetically Modified plants. (Enhs. umn. edu, 2013) Another health concern for Genetically Modified foods is an increase is food allergies. Food Allergy affects approximately 6% of children and 3% of adults in Australia and lately has become a major public health issue (Bakshi, 2003). Allergic reactions occur when a usually harmless proteins enter the body and causes an immune response (Bernstein et al., 2003). If the protein in a Genetically Modified food originates from a source that is known to cause allergic reactions in humans or a source that has never been consumed by humans as food, the protein could evoke the immune response in humans increases. No allergic reactions to Genetically Modified foods by the public have been confirmed, evidence suggesting that some Genetically Modified food products could cause an allergic reaction has motivated a number of biotechnology companies to discontinue their development (Bakshi, 2003). Another serious concern for Genetically Modified foods is the production of â€Å"super bugs†, scientists are finding that Genetically Modified crops are a breeding ground for bacteria and virus’s and that they are extremely resilient to antibiotics and able to overrun the â€Å"good† bacteria in a healthy humans digestive system causing severe and irreversible damage after they have been consumed through Genetically Modified foods, there is documented proof that the digestive system of lab controlled mice fed these â€Å"super bugs† become enlarged and caused the mice to die after it’s digestive track was over run by the bacteria in turn causing its immune system to weaken. Government authorities across the world have strict regulations in place on genetically modified foods. In the U. S, agencies such as the Environmental Protection Agency and the Food and Drug Administration supervise projects that involve Genetically Modified crops. Although the U. S government doesn’t require farmers and retailers to label Genetically Modified foods, each product must go through a strict regulation test in order to be sold to the public. (Curiosity, 2013) Genetically Modified foods are new to the Australian food supply, a cautious and in depth approach is taken when assessing the safety of Genetically Modified foods for consumption by humans. FSANZ (Food Standard Australia and New Zealand) carry out safety checks on a CBC (case by case) basis, this means each new Genetic Modification is assessed individually for any potential impact on the foods safety, â€Å"We compare the Genetically Modified food with a similar, commonly eaten conventional food from a molecular, toxicological, nutritional and compositional point of view. The aim is to find out if there are any differences between the GM food and its conventional counterpart, which we already know to be safe to eat. † -FSANZ official (Foodstandards. gov. au, 2013) Although there are many health issues concerning Genetically Modified foods, rigorous and in-depth research has been done to ensure Genetically Modified foods that are available to the public are totally safe and healthy to be consumed, as more and more foods are becoming Genetically Modified more safe and sustainable procedures are being put in place to ensure that the public and the environment benefit from Genetically Modified Foods.

Monday, September 16, 2019

The Differences between the Empire State Building and Burj Al-Arab Hotel

The differences between Empire State Building and Burj Al-Arab Hotel There are two celebrated edifices in the universe, called Empire State Building and Burj Al-Arab Hotel. Empire State Building is located in New York, and it is one of the tallest constructions in New York, even in the universe. Another one of the universe tallest edifices is Burj Al-Arab Hotel, it is located in Dubai. In this essay, I will compare and contrast them in history, uses and being celebrated. In the Empire State Building’s history, it is 1250 pess tall and was the tallest edifice in the universe when it was built in 1931. At that clip, it was non merely go a landmark of New York, but besides became a symbol of accomplishing the impossible. There was a skyscraper race in the universe in 20 century. Walter Chrysler, the laminitis of the Chrysler Corporation, was building a monumental edifice, the tallness of which he was maintaining secret until the edifice ‘s completion. John Jakob Raskob, antecedently a frailty president of General Motors, decided to fall in this race, and he wanted to crush Chrysler. Not cognizing precisely what height he had to crush, John started building on his ain edifice, the Empire State Building. The Empire State Building completed with an astonishing effort that the full edifice was constructed in merely one twelvemonth and 45 yearss and merely cost around 41 million dollars ( Jennifer Rosenberg ) . Similarly, there are besides many glorifications in the history of Burj Al-Arab Hotel. For illustration, it was the tallest sea-based hotel in the universe at a tallness of 321 metres when it was completed in 1999. As the ground of edifice Burj Al-Arab Hotel is wholly different with the Empire State Building, that the authorities of Dubai wanted a edifice that would go an iconic or symbolic statement with the name of the state, merely as what it has been. The design of Burj Al-Arab Hotel was inspired by the wind-filled canvass of an Arab trading dhow ship, and that is why it is built on an unreal island. Unlike the Empire State Building, the building of Burj Al-Arab Hotel cost a big sum of money and clip that it was built in 1994 and be around 650 million dollars to construct. And this money made it go the coal of the Leading Hotels of the World ( Rick Archer ) . The Empire State Building is built as an office edifice, so the primary use is supplying office infinites for companies. But because it is located on the most comfortable parts of Manhattan Island, the rent of office infinites is expensive. Even though the rent is excessively dearly-won, the major companies of different countries, such as finance, touristry and insurance, lease an office in the Empire State Building, because of its celebrated and demoing the capacities of their companies. In add-on, the Empire State Building is known by the universe, so it becomes one of the most celebrated tourer attractive forces in New York. For absorbing more tourers, there are different sorts of exhibitions in the museum of the Empire State Building. Of class, many sorts of bars and nines are necessary, and tourers can see all attractive forces in New York in several proceedingss ( Empire State Building ) . However, as a hotel, the uses of Burj Al-Arab Hotel are about different with the Empire State Building, it is built for touristry. But because Dubai wanted to do it go an iconic, the Burj Al-Arab Hotel was absolutely built with strong Islamic manner, excessive decor and high engineering ( Burj Al-Arab Hotel ) . Similar to the Empire State Building, this makes it go one of the most celebrated and the most expensive hotels in the universe, the every night rates start merely north of $ 1500. Both Empire State Building and Burj Al-Arab Hotel have a phase on the acme of them, although the phase of Burj Al-Arab Hotel is a rooftop helipad. So if you are affluent plenty to populate in it, the hotel besides offers chopper service from the airdrome to hotel ( Justin Delaney ) . As we know, the Empire State Building is the world’s most celebrated office edifice, but I want to inquire, why does it go such celebrated? And I found out that it is celebrated by its tallness and films. And the major ground is from the clip it was built in the 1930 ‘s to the edifice of the World Trade Center towers in the 1970 ‘s it was the tallest edifice in the universe, even now it still ranks among the top 10 and is the tallest edifice in New York ( Why is the Empire State Building celebrated? ) . Furthermore, the film that made it celebrated isKing Kong, one of the most noteworthy films in American history. In this film, the originalKing Kongof 1933 used a theoretical account of the newly-completed Empire State Building for Kong to mount at the flood tide ( What film made the Empire State Building celebrated? ) . This image non merely made the Empire State Building noticed by the universe, but besides became the most authoritative scene ofKing Kong. Similarly, Burj Al-Arab Hotel used to be world’s tallest hotel, but now it is still the world’s 2nd tallest hotel. on the other manus, it is non simply celebrated by its tallness, its expensiveness is besides celebrated in the universe. For illustration, the monetary value of a Royal suite is 20 1000 dollars, per dark. The monetary value can make the cost of a mid-sized saloon, doing it one of the universe ‘s most expensive suites, even a smallest room besides needs 1500 dollars. But the expensiveness is sensible, because the installations and helping of Burj Al-Arab Hotel are the best in the universe. For case, when the clients of Burj Al-Arab Hotel go out of the airdrome, they have two lavish picks: travel to hotel by Rolls Royce saloons or chopper. If you choose helicopter, you will hold a opportunity to watch the Dubai from sky in 15 proceedingss. Those are the grounds why they have a batch of clients, even the suites are expensive ( Burj Al-Arab Hotel ) . Why did I want to compare the Empire State Building and Burj Al-Arab Hotel? Because these two edifice represent the people who live in different period and different states. The Empire State Building shows America had become one of the most affluent states in 1930, and American people liked to demo their power and wealth. For the Burj Al-Arab Hotel, it shows the Dubai had an outstanding economic system, and the Arabs more attention about their state After comparing the Empire State Building and the Burj Al-Arab Hotel in three different ways, I found out: In history, they were built for different intents, the Empire State Building was built for a personal glorification, but the Burj Al-Arab Hotel was built because of the dream of doing a landmark for Dubai, but likewise, both of them used to be the tallest edifice in their types ; in uses, both constructions link to the local touristry, although the Empire State Building besides provides offices to companies ; in being celebrated, both of them are celebrated for their tallness, nevertheless, the Empire State is besides celebrated by a film,King Kong, and the Burj Al-Arab Hotel is besides celebrated for its expensiveness and helping. Overall, even though they are similar in some parts, they still represent different images of their states to the universe. Work Citedâ€Å"Burj Al-Arab Hotel† . baike.com Feb 11 2014hypertext transfer protocol: //www.baike.com/wiki/ % E9 % 98 % BF % E6 % 8B % 89 % E4 % BC % AF % E5 % A1 % 94 % E9 % 85 % 92 % E5 % BA % 97â€Å"Empire State Building† . Baike.com Feb 11 2014hypertext transfer protocol: //www.baike.com/wiki/ % E5 % B8 % 9D % E5 % 9B % BD % E5 % A4 % A7 % E5 % 8E % A6Jennifer Rosenberg. â€Å"The Empire State Building † . About.com. Feb 9 2014.hypertext transfer protocol: //history1900s.about.com/od/1930s/a/empirestatebldg.htmJustin Delaney. â€Å"Dubai ‘s iconic Burj Al Arab – the universe ‘s most glamourous hotel † . gadling.com. Jun 21 2011.hypertext transfer protocol: //www.gadling.com/2011/06/21/the-iconic-burj-al-arab-the-worlds-most-glamorous-hotel/Rick Archer. â€Å"The Most Beautiful Hotel in the World † . ssqq.com. July 2004hypertext transfer protocol: //ssqq.com/archive/vinlin23.htmâ€Å"What film made the Empire State Building celebrated? † wiki.answers.com Feb 11 2014hypertext transfer protocol: //wiki.answers.com/Q/What_movie_made_the_Empire_State_Building_famous # slide=3 & A ; article=What_movie_made_the_Empire_State_Building_famousâ€Å"Why is the Empire State Building celebrated? † wiki.answers.com Feb 11 2014hypertext transfer protocol: //wiki.answers.com/Q/Why_is_the_Empire_State_Building_famous # slide=7 & A ; article=Why_is_the_Empire_State_Building_famous

Sunday, September 15, 2019

Outline the Cosmological Argument for the Existence of God (21)

Outline the cosmological argument for the existence of God (21) The Cosmological argument is an argument that attempts to prove the existence of God, it is also known as the causation argument which argues that as all events require a cause, if the universe is an event it must have a cause and that cause is God. The argument is a posteriori because its based on evidence that already exists in the universe. The cosmological argument is also inductive because the conclusion is what is most probable, it is also synthetic because the truth can only be determined by experience. Cosmological’ comes from the Greek words ‘kosmos’ and ‘logos’ translated as ‘cosmos’ synonymous with ‘universe’ and ‘Logos’ meaning ‘blueprint’ or ‘plan’. Therefore, ‘cosmology’ refers to the ‘blueprint of the universe’. The Cosmological argument originated from Plato and Aristotle however it was mainly later developed by St. Thomas Aquinas. Their arguments both began with the idea that motion needs a prior agency. Plato then identified the first cause of the chain of events as the need for an unmoved mover which started off the chain.Aquinas' main argument is well known as ‘Aquinas' third way'; the argument from contingency and necessity. The first of Aquinas' ways was ‘from motion,' this follows the idea that all objects move and a change of quality is movement. Nothing can move itself, which then leads to the idea of a chain of movement but the chain cannot be infinate, therfor there must be an unmoved mover to begin the chain. This first mover is God. The second of Aquinas' ways was ‘from efficiant causes,' this follows the idea that all things are caused by something else because they cant cause themselves or they would exist before themselves.However this would mean that there cant be an infinite chain of causes, meaning there must be a 1st cause that caused all causes, then this 1st cause is God. The third of Aquinas' ways is ‘from contingency and necessity. This follows the idea that everything is dependant of factors outside itself, therefor everything is contingent. If this is correct then there must be a necessary being upon which everything is dependant on. The necessary being is God.Another part to the cosmological argument is the Kalam argument which was developed by Al Ghazali and recently developed by Craig. The Kalam argument rejects the idea of an actual infinite because an actual infinite past of the universe is impossible. Craig developed the Kalam argument and added that it is logically unsound to propose an infinite series because for this to actually occur we would have to have travelled an infinite length of time and so still wouldnt be in the present yet.However, some would critique Aquinas’ theory, for example; Hick pokes holes in aquinas's ‘three ways. ’ Hick says that Aquinas p resent us with two alternatives; that the universe is either â€Å"a fact†, or there is a ‘first cause’. Aquinas' argument can only be proven if there is evidence of a first cause of the universe. (ii )Consider the view that the strengths are more convincing than the weaknesses (9) Leibniz argued that there had to be a sufficient reason for the universe to exist which supports Aquinas's theory.Leibniz says that even if the universe had always been in existence, it would still require an explanation for its existence so we can establish that there is something rather than nothing. Since there is nothing within the universe to show why it exists the reason must therefor exist outside of it. However Hume disagrees with Aquinas and observes that to arrive at the existance of god from the premises of the cosmological argument, this requires an inductive leap which ineffectively guesses without having actual evidence that allows for the assumption to be made.This then means that you cannot make an inductive leap about the universe because we cannot make conclusions about something outside our exerience. In contrast to Hume copelston suports Aquinas' rejection of infinite regress based on the idea that an infinite chain of contingent beings would only consist of contingent beings therefor meaning they could never be able to bring themselves into existence. However like Hume, Mackie disagrees with Aquinas' inductive leap by stating hat ‘ everything at some time must exist' to ‘at some point sometime everything does not exist' here there is a clear overlap of things that just dont make sense to put after eachother as there is clearly something missing in the middle. Taking these points into consideration we can make the assumption that the weaknesses are in actual fact stronger than the strengths because the strenghts agree with the inductive leap aquinas has made, however the leap clearly looks as if something in the middle is missing a s you just cant make an assumption on something bigger than us that we have no expience of.

Saturday, September 14, 2019

We are the Champions

For as long as I can remember, I have loved and played organized basketball. The culmination of this adoration and dedication came during my senior year of high school when we won the state championship. I spent most of my childhood and adolescent years watching, practicing and playing this game. I played through all kinds of injuries and illnesses. I played with all kinds of organizations and teams. Now, I was the captain of the team of all teams: State Champions.I'd reached the manacle of my basketball career. If we are looking at this significant event through the behavioral perspective of psychology, we see the ways in which it applies. The behavioral perspective allows us to look at the obvious observable and measurable behaviors as opposed to the internal and mental ones. It focuses on how behaviors are learned and reinforced. Practice was the driving behavior that allowed our team to succeed. Our coaches required us to practice the same plays over and over again. We practiced shooting drills over and over again.These things were reiterated until hey became second nature, and then we practiced them some more. Our philosophy was that we did not practice until we got it right, but we practiced until we could not get it wrong. Also, part of our preparation included watching videos of our opponents. This allowed us to learn their behaviors and tendencies in order to devise a plan to counteract them (Baron & Kessler, 2008). During the game of basketball, the cognitive perspective plays an important role. This perspective is concerned with the mental function: how things are perceived, remembered, reasoned, decided, or problem solved.Before the game starts, a strategy is developed for the offensive and defensive side of the court. It has to be remembered by every member of the team along with all of the plays and signals to help the team function as one cohesive unit. We are also tasked with making split second decisions throughout the game in order to navigate the opponent's defensive scheme (McLeod, 2007). Through this entire process, I learned that hard work would lead to great rewards. One of the ways this happened was through classical conditioning learning.This type of learning involves â€Å"placing a neutral signal before a naturally occurring reflex† (Baron & Kessler, 2008, p. 161). In order to build our stamina to run up and down the court for a complete game, our coaches used a whistle. When the whistle was blown, we were required to run suicide drills. At the sound of a double whistle, we were required to stop running. The blowing of the whistle is an unconditioned stimulus and the act of running is an unconditioned response. Operating learning came in the form of positive reinforcements and punishments.We were praised and received gifts for working hard in practice, for performing drills ND tasks flawlessly, and for meeting seasonal milestones. Our punishments came in the form of performing push-ups or having an extra early morning practice when we did not do what was expected. In addition, some of my basketball skills were acquired through observational learning. I watched Just as much basketball on television as I played. I took some of the things that I saw my favorite college and professional basketball players performed and worked to mimic them (Baron & Kessler, 2008).This entire senior basketball season was very memorable. It was like ale with a story book ending. However, some of the details of that season was lost. This is because of retroactive interference. We played 23 games that year, and each game added a new memory. Because of the similarities in games, the details get clouded with the addition off new one. The championship game was different. That game is an autobiographical memory as it was a reward for what I had worked so long to achieve. This was the most important thing that Vive done up until that point.

Friday, September 13, 2019

Ethical obligations Essay Example | Topics and Well Written Essays - 750 words

Ethical obligations - Essay Example Hence there is a great amount of responsibility that goes within their working basis. They know that if they falter, there is someone else to take their seat and the public would never approve of them in the first place. It is this accountability factor that asks of them to give in their best time and time again. What is most significant is the fact that public administrators have an ethical obligation to perform, mostly on all of the occasions where they get in touch with the public. It goes to suggest without much exclamation that public administrators face ethical responsibilities because it is the public that they have to hold fast on to. They know that if the public does not get the benefits from their undertakings, it would be a futile exercise to work their way through different tasks and actions. The public administration implications in taking good care of the public health sector, housing, education and others is centered on the premise of the peculiar reinforcement strateg ies. These are followed in a very proactive fashion and that too on a consistent rate. The reinforcement phenomenon gets implemented when there are situations which ask of the public administrators to give in their very best on a constant basis. ... he domains of the public administrators, the people resourcing discussion is based on the tangent of giving more significance to the people who are more skilled and who get the most work done in an efficient capacity. However these elements must come with an ethical obligation attached with the same (Bertucci 2006). This means that the public administration implication is made stronger with each passing day and the reinforcement strategies with the help of the motivational reward hierarchies working towards the eventual benefit of the public at large. Administering people with an ethical responsibility thus becomes precisely an easy task as it manifests sound objectives in a quick manner. Thus the public administration implication of administering people through the assistance of the reinforcement strategies is a difficult proposition if the public administrator does not carry out his homework in a well-cohesive fashion. He must know what he is propagating and that too at the right l evels, on a consistent basis. There are a few instances when the public trusts the administration that has been given the right to serve them, and this is indeed an aspect which could be seen in the positive aspects under the relationship between the two – the public and the public administrators. The recent trends in privatizing government functions has a dilemma attached to it, especially when one considers the case related with the attainment of public interest and the like. What this does is to make sure that privatization remains the key within the understanding of the public that it exists to bring harmony within their ranks and not to make them feel indifferent to privatization or even experience numbness towards it. Privatization within the public administration regimes is

Thursday, September 12, 2019

Baptism in Fifth Business Essay Example | Topics and Well Written Essays - 1000 words

Baptism in Fifth Business - Essay Example This idea did not take hold in the religions of the Graeco-Roman world, but firmly established itself in Judaism. It is from there that baptism became an important part of the Western tradition.   Ã‚  According to the Hebrew Bible a person can become 'unclean' for the purposes of performing various rituals by contact with certain substances vile in the opinion of ancient Hebrew priests, for example semen (Lev 15:13-17) or menstrual blood (Lev 15:19-30). In some way this must have begun as a practical consideration, but it soon took on a more symbolic use as the practical action became a ritual, and the logic of the ritual became more extensive. The high priest was able, through analogy, to be baptized for the entire community and wash away their sins which rendered them unclean for ritual purposes and thus unfit for worshiping Yahweh (Lev 16:24).   Although this ritual action of baptism has a metaphorical basis, it remained part of the 'nuts and bolts' of religious action. Christ ianity moved it to a different sphere. Although the program of John the Baptist is far from clear, he seems to have carried out the traditional baptism for cleaning away the sins of the nation, but believed that the nation as a whole, rather than merely the high priest, had to be baptized (Matt 3; Lk 3; Jn 1:19-36). At some point between John's baptizing and the writing of the Gospels, baptism took on a spiritual dimension so that it would not only wash away uncleanness and sin, preparing one for ritual action, but was meant to transform.

Wednesday, September 11, 2019

Organizational Culture Analysis Research Paper Example | Topics and Well Written Essays - 750 words

Organizational Culture Analysis - Research Paper Example It is the hope of this author that such a level of discussion will be beneficial to the reader in terms of helping them to gain a greater understanding, not only the particular store in question, or the retail chain, but the way in which culture is oftentimes represented America. Firstly, with respect to the observable artifacts, it was clear and apparent from day one that the level and type of interaction with the consumer was the primary drive that all of the human resources literature and media consisted of. I distinctly remember the hours of video training that were required prior to even beginning the job in question. For instance, each and every situation that was presented, with the exception of those situations that involved fellow coworkers, was concentric upon maximizing the satisfaction of the consumer and minimizing the difficulties or negative emotions that an employee might represent. In retrospect, it is obvious that all of this was performed as a means of ensuring that profitability remained at a maximum. As the old saying goes, â€Å"the customer is always right†. Ultimately, this particular quote was incorporated within the training literature and served as a backbone with respect to the way in which the employees/stakeholders sought to go about their daily tasks. An espoused value that was promoted heavily within the organization was with respect to the ethical conduct that employees represented. Whereas it is oftentimes the case that individual employers hammer home such issues as the need to come to work on time, the importance and relevance of abstaining from racist, sexist, or ageist language and actions, or the need to give more time and energy to the details of one’s labor, the particular workplace in question had an espoused value system that was almost entirely concentric upon ethics (Baack, 1998). Although it is true that they engaged with the other topics that have been referenced above, the

Contemporary Communications Assignment Example | Topics and Well Written Essays - 1500 words

Contemporary Communications - Assignment Example However, in communicating with others and preparing for your career, all scholars need to know what communication skills they do and do not have and which ones need improvement. Within the education of communicating and interacting with others educators assist their students in understanding personal skills inventory charts to look at where the person may need to look at some of their own concerns that may be hindering them from being a person who communicates well and without seeming defensive or unprofessional, who can take care of business, and gets a job, special request, and tasks done with little effort and eventually within their new career. Having control and knowing what strategies and techniques you are good at and can apply at work will benefit the company and make you a stronger person in your position and help build the worker’s morals and ethics while being able to handle situations that may not always be pleasant will prepare you to control and handle future iss ues and problem-solving with others. First, people must become educated on what communication skills they have, which ones they are good at, which ones they no little or nothing about, learn about them, practice them when working and interacting with others to make conversing and working with other people easier regardless if it as home, in a social setting, and especially in meetings with superiors, working with co-workers, and being able to be an asset to whatever project you want to implement. One of the biggest communication skills that most people understand and become aware of first is when the student is in school, yet have already been taught by their parents and other caregivers, which is simply conveying a message to another person. However, a lot of times it is not the message that one person wants to say to another it is how they say it that makes a conversation go sour and get nowhere fast. If people have issues just getting their point across then that is telling them they do need to reevaluate how they talk to others, as well as look at other communication skills.   Some personalities clash because people are different, yet in the professional world most people learn to respect that others are different, and that is the whole reason that makes that person who they are, so many of these people who work as a team, will do what they can to get along with others because they know that regardless of what they do the other person is not going to come around and they are big enough to overlook it.